
Calculate founder effects for significant peaks
qtl_effects.RdCalculate founder effects for significant peaks
Usage
qtl_effects(
peaks,
mapping,
suggLOD = 6,
outdir = NULL,
effects_out = "effects.rds",
total_cores = NULL,
save = "sr"
)Arguments
- peaks
List of dataframes containing annotated QTL peaks for each tissue, or full path to
.rdscontaining one.- mapping
Mapping list from
mapQTL, or full path to.rdscontaining one.- suggLOD
Suggestive LOD threshold to use for filtering phenotypes. Default is 6.
- outdir
Directory to save effects output files. Default is
NULL.- effects_out
String indicating the name of the output file containing founder haplotype effects results. This file will be saved in
.rdsformat and used for downstream analysis and visualization. Should end in.rds. Default is "effects.rds"- total_cores
Number of available cores to use for parallelization. Default is
NULL.- save
Indicates object return/save behavior. One of
c("sr", "so", "ro"); save & return, save only, return only. Default is "sr".
Value
A list containing:
effects_blupQTL effect BLUPs from scan along one chromosome. Output from
qtl2::scan1blup()peaksannotated peaks with LOD scores above suggestive threshold